Wesley Blake was born and raised in the Texas hill country. He began acting on stage in 2003 at the age of 26. Soon after, he moved into independent short and feature length film. He has been featured in several music videos including Seether's "Country Song" and Rich O' Toole's "In a Minute or Two."

In 2008, Wesley appeared in a leading role as Jack Heart in The Innocence Saga, a 10 film epic entirely shot in one year.