Levitas' feature film directorial debut Lullaby, from his own screenplay, stars Amy Adams, Richard Jenkins, Terrence Howard, Jennifer Hudson, and Garrett Hedlund. The film, an exploration of patients' rights, was described by Pete Hammond (Deadline) as a "strong human drama" with "Jenkins a true actor's actor, delivering a very Oscar-worthy supporting turn."

Levitas' latest directing project Minamata follows photojournalist W. Eugene Smith who takes on a secret commission by Life magazine and travels to the Japanese coastal town of Minamata to expose corporate negligence and government cover-ups by documenting one of the world's most horrifying environmental disasters.

Levitas has also produced The White Crow (Ralph Fiennes, Adele Exarchopoulos), My Zoe (Julie Delpy, Daniel Brühl, Gemma Arterton), Georgetown (Vanessa Redgrave, Annette Bening), Farming (Kate Beckinsale, Gugu Mbatha-Raw), The Gateway (Bruce Dern, Olivia Munn, Frank Grillo), and The Quarry (Michael Shannon) among others.

Levitas maintains studios in New York and London. He is Global Patron of The Wilderness Foundation.